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UAMC 00039 dihydrochloride

CAS No. 697797-51-6

UAMC 00039 dihydrochloride ( UAMC00039, UAMC 00039, UAMC-00039 )

Catalog No. M17570 CAS No. 697797-51-6

UAMC00039 dihydrochloride is a potent, reversible and competitive dipeptidyl peptidase II inhibitor with an IC50 of 0.48 nM.

Purity : 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    UAMC 00039 dihydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    UAMC00039 dihydrochloride is a potent, reversible and competitive dipeptidyl peptidase II inhibitor with an IC50 of 0.48 nM.
  • Description
    UAMC 00039 dihydrochloride is a potent inhibitor of dipeptidyl peptidase II (DPP-II) (IC50 = 0.48 nM). UAMC 00039 dihydrochloride exhibits selectivity for DPP-II against DPP-9, DPP-8 and DPP-IV (IC50 values are 78.6, 142 and 165 μM, respectively).
  • Synonyms
    UAMC00039, UAMC 00039, UAMC-00039
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    Topoisomerase
  • Recptor
    Dipeptidyl peptidase II
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    697797-51-6
  • Formula Weight
    382.76
  • Molecular Formula
    C16H26Cl3N3
  • Purity
    98%
  • Solubility
    DMSO : ≥ 150 mg/mL; 391.89 mM
  • SMILES
    C1CCN(CC1)C(=O)[C@H](CCNCc1ccc(cc1)Cl)N.Cl.Cl
  • Chemical Name
    (2S)-2-Amino-4-[[(4-chlorophenyl)methyl]amino]-1-(1-piperidinyl)-1-butanone dihydrochloride

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Maes MB, et al. In vivo effects of a potent, selective DPPII inhibitor: UAMC00039 is a possible tool for the elucidation of the physiological function of DPPII. Adv Exp Med Biol. 2006;575:73-85.
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